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Guillermo L Chantada Selected Research

Topotecan (Hycamtin)

10/2017Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier.
1/2017OCULAR PHARMACOLOGY OF CHEMOTHERAPY FOR RETINOBLASTOMA.
10/2016Sustained-release hydrogels of topotecan for retinoblastoma.
1/2016Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells.
9/2014Ocular pharmacology of topotecan and its activity in retinoblastoma.
4/2014Clinical pharmacokinetics of intra-arterial melphalan and topotecan combination in patients with retinoblastoma.
5/2013Intra-arterial chemotherapy is more effective than sequential periocular and intravenous chemotherapy as salvage treatment for relapsed retinoblastoma.
3/2013Ocular and systemic toxicity of intravitreal topotecan in rabbits for potential treatment of retinoblastoma.
6/2012Pharmacokinetic analysis of melphalan after superselective ophthalmic artery infusion in preclinical models and retinoblastoma patients.
4/2010Episcleral implants for topotecan delivery to the posterior segment of the eye.
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Guillermo L Chantada Research Topics

Disease

36Retinoblastoma (Glioblastoma, Retinal)
11/2022 - 03/2004
23Neoplasms (Cancer)
01/2022 - 07/2007
5Neuroblastoma
12/2021 - 03/2004
4Sepsis (Septicemia)
01/2018 - 03/2010
3Disease Progression
10/2021 - 03/2010
3Neoplasm Metastasis (Metastasis)
11/2019 - 07/2007
3Neutropenia
01/2018 - 05/2013
3Margins of Excision
11/2014 - 02/2009
2Edema (Dropsy)
01/2018 - 04/2009
1COVID-19
10/2021
1Necrosis
01/2019
1Thrombosis (Thrombus)
01/2018
1Fever (Fevers)
01/2018
1Hypotension (Low Blood Pressure)
01/2018
1Bradycardia
01/2018
1Thrombocytopenia (Thrombopenia)
01/2018
1Melanoma (Melanoma, Malignant)
11/2017
1Sarcoma (Soft Tissue Sarcoma)
11/2017
1Neurilemmoma (Schwannoma)
11/2017
1Lymphoma (Lymphomas)
11/2017
1Toxic Optic Neuropathy
10/2016
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2016
1Lung Neoplasms (Lung Cancer)
01/2016
1Body Weight (Weight, Body)
04/2014
1Non-Hodgkin Lymphoma (Lymphosarcoma)
10/2012
1Stevens-Johnson Syndrome (Lyell's Syndrome)
10/2012
1Renal Insufficiency (Renal Failure)
10/2012
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2012
1Vomiting
04/2009
1Herpes Simplex
07/2007
1Medulloblastoma
03/2004
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
03/2004

Drug/Important Bio-Agent (IBA)

13Topotecan (Hycamtin)FDA LinkGeneric
10/2017 - 03/2004
6Pharmaceutical PreparationsIBA
01/2022 - 03/2004
6Melphalan (Alkeran)FDA LinkGeneric
01/2018 - 06/2012
5Messenger RNA (mRNA)IBA
12/2016 - 03/2010
4Carboplatin (JM8)FDA LinkGeneric
11/2022 - 07/2007
4(N- acetylneuraminyl)- galactosylglucosylceramide N-acetylgalactosaminyltransferaseIBA
01/2019 - 03/2010
4Retinaldehyde (Retinal)IBA
11/2017 - 03/2013
2Etoposide (VP 16)FDA LinkGeneric
11/2022 - 03/2004
2Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2016
2Transcription Factors (Transcription Factor)IBA
12/2016 - 07/2015
2racotumomabIBA
01/2016 - 12/2015
2GangliosidesIBA
12/2015 - 03/2010
2GD2 gangliosideIBA
09/2013 - 03/2010
1Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
11/2022
1Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA
01/2022
1CytokinesIBA
01/2022
1Immune Checkpoint ProteinsIBA
01/2022
1Macrophage Migration-Inhibitory FactorsIBA
01/2022
1Conditioned Culture MediaIBA
01/2022
1dinutuximabIBA
12/2021
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
12/2021
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
12/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2020
1ParaffinIBA
01/2020
1Forkhead Transcription Factors (Forkhead Box Proteins)IBA
01/2020
1RNA (Ribonucleic Acid)IBA
01/2018
1Pantoprazole (Protonix)FDA LinkGeneric
10/2017
14- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)IBA
01/2017
1HydrogelsIBA
10/2016
19 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA
10/2016
1GlycoconjugatesIBA
01/2016
1aluminum sulfate (alum)IBA
01/2016
1Immunoglobulin G (IgG)IBA
01/2016
1VaccinesIBA
12/2015
1Digoxin (Digitek)FDA LinkGeneric
07/2015
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
09/2013
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2012
1CreatinineIBA
10/2012
1Phosphates (Orthophosphate)IBA
10/2012
1LactonesIBA
04/2010
1EnzymesIBA
03/2010
1Ondansetron (Zofran)FDA LinkGeneric
04/2009
1Phosphotransferases (Kinase)IBA
07/2007
1Ganciclovir (Cytovene)FDA LinkGeneric
07/2007

Therapy/Procedure

17Drug Therapy (Chemotherapy)
11/2022 - 03/2004
12Therapeutics
11/2022 - 05/2005
7Radiotherapy
11/2022 - 07/2010
5Conservative Treatment
01/2022 - 05/2014
3Immunotherapy
01/2022 - 12/2015
3Intravitreal Injections
01/2018 - 09/2014
3Adjuvant Chemotherapy
11/2014 - 07/2007
2Injections
01/2018 - 03/2013
2Cryotherapy (Therapy, Cold)
01/2018 - 07/2007
2Intraocular Injections
05/2013 - 08/2007
1Stem Cell Transplantation
10/2021
1Neoadjuvant Therapy
01/2018
1Anesthesia
01/2018
1Induction Chemotherapy
07/2015
1Salvage Therapy
05/2013
1Aftercare (After-Treatment)
10/2012
1Intravenous Infusions
08/2007
1Induced Hyperthermia (Thermotherapy)
07/2007
1Brachytherapy
07/2007
1Light Coagulation
07/2007
1Lasers (Laser)
07/2007